Multidrug-ResistantCorynebacterium striatumAssociated with Increased Use of Parenteral Antimicrobial Drugs

Multidrug-Resistant Corynebacterium striatum Associated with Increased Use of Parenteral Antimicrobial Drugs

resistant bacteria. We retrospectively identified 179 isolates in a clinical database. Clinical relevance, in vitro susceptibility, and length of parenteral antimicrobial drug use were obtained from patient records. For patients with hardwareor device-associated infections, those with C. striatum infections were matched with patients infected with coagulase-negative staphylococci for case–contr...

Clinical pharmacology of parenteral use of antiepileptic drugs.

Intravenous (i.v.) administration of antiepileptic drugs (AEDs) produces the most rapid onset of action, as it is delivered directly into the bloodstream and immediately produces maximal plasma concentration (C0 = Cmax). In addition to its therapeutic value, i.v. administration is essential in investigating the pharmacokinetics (PK) or clinical pharmacology of drugs, as it bypasses absorption a...

The use, appropriateness and outcomes of outpatient parenteral antimicrobial therapy.

OBJECTIVE Outpatient parenteral antimicrobial therapy (OPAT) is increasingly used to treat children at home, but studies in children are scarce. We aimed to describe the use, appropriateness and outcomes of OPAT in children. DESIGN This was a 12-month prospective observational study. SETTING The hospital-in-the-home programme of The Royal Children's Hospital Melbourne. PATIENTS All patien...

Use of Cytotoxic Drugs

استفاده روز افزون از داروهای سایتوتوکسیک باعث شده است که پرستاران بیشتر در معرض خطرات این مواد باشند. از این رو خانم جونیت گیبز ضمن مطالعه و بررسی در این زمینه راه هایی را جهت به حداقل رساندن این خطرات مطرح می کند.  

Outpatient parenteral antimicrobial therapy.